Dynamin 1 anticorps (pSer778)
Aperçu rapide pour Dynamin 1 anticorps (pSer778) (ABIN319106)
Antigène
Voir toutes Dynamin 1 (DNM1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer778
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Specificité
- This antibody is specific for Dynamin when phosphorylated at serine 778.
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Purification
- Affinity chromatography
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Immunogène
- Synthetic phosphopeptide corresponding to an amino acid sequence within dynamin which includes phosphorylated Ser778.
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Isotype
- IgG
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Indications d'application
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Western Blot: 1: 1000, detects a band of approximately 95 kDa in rat hippocampus lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Dynamin 1 (DNM1)
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Autre désignation
- Dynamin-1
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Sujet
- Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.Synonyms: DNM, DNM1
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ID gène
- 140694
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NCBI Accession
- NP_542420
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UniProt
- P21575
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Pathways
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
Antigène
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