GRIA2 anticorps

N° du produit ABIN319147

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIA2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Poisson zèbre (Danio rerio), Poulet et Singe.

Aperçu rapide pour GRIA2 anticorps (ABIN319147)

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Poulet, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRIA2 anticorps

Specificité: This antibody is specific for glutamate receptor subunit 2 (GluR2), a component of the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid) group of ionotropic glutamate receptors, which play a key role at excitatory synapses, including synaptic transmission, stabilisation and plasticity.

Purification: Affinity chromatography

Immunogène: Keyhole limpet haemocyanin conjugated synthetic peptide corresponding to an amino acid sequence within rat GluR2.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain hippocampuscell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM Hepes, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin, 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: Glutamate Receptor 2 / GLUR2

Sujet: GluR2 is possibly the most important of the AMPA receptor subunits, responsible for AMPA receptor rectifying properties, control of ion flow and in particular the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2(R) form, containing a critical arginine residue (as opposed to a glutamine residue) in the Transmembrane region 2 (TM2) domain, thereby rendering native AMPA receptors impermeable to calcium.Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic

ID gène: 2891

NCBI Accession: NP_000817

UniProt: P42262

Pathways: Signalisation PI3K-Akt