MAP1LC3A anticorps (N-Term)

N° du produit ABIN319367

L’anticorps anti-MAP1LC3A Polyclonal Lapin est utilisé pour la détection de MAP1LC3A dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IF.

Aperçu rapide pour MAP1LC3A anticorps (N-Term) (ABIN319367)

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP1LC3A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-MAP1LC3A anticorps

Épitope: N-Term

Séquence: MPSDRPFKQR RSFA

Specificité: This antibody detects endogenous levels of total LC3A/MAP1LC3A protein.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse and Rat

Purification: Immunoaffinity Chromatography using epitope-specific immunogen

Immunogène: The antiserum was produced against a synthesized peptide Corresponding to the amino terminal sequence from Human LC3A protein.

Information d'application

Indications d'application: Western blot: 1/500approx. 1/1000. Immunofluorescence: 1/100approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at-20 °C.

Détails sur MAP1LC3A

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Autre désignation: LC3

Sujet: Microtubule-associated MAPILC3A constitutes nearly half of the mass of all the microtubule associated proteins that copurify with brain microtubules. MAP1LC3A is one of three human orthologs of the rat Map1LC3, (named MAP1LC3A, MAP1LC3B, and MAP1LC3C). The three isoforms of human MAP1LC3 exhibit distinct expression patterns in different human tissues and also differ in their post-translation modifications. MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue, MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form.Synonyms: Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3A, MAP1 light chain 3-like protein 1, MAP1A / 1B light chain 3 A, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1LC3A, Microtubule-associated protein 1 light chain 3 alpha, Microtubule-associated proteins 1A/1B light chain 3A

ID gène: 84557

NCBI Accession: NP_115903

UniProt: Q9H492

Pathways: Autophagy