VCAM1 anticorps (FITC)
Aperçu rapide pour VCAM1 anticorps (FITC) (ABIN319848)
Antigène
Voir toutes VCAM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises Human VCAM-1, a 110 kDa molecule whose ligand is VLA-4. The antigen is expressed on activated endothelial cells and some tissue macrophages, bone marrow fibroblasts and myoblasts.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity Chromatography on Protein G.
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Isotype
- IgG1
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Indications d'application
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Flow Cytometry: use 10 μL of neat-1/10 diluted antibody to label 10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 0.1 % BSA as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Autre désignation
- CD106 / VCAM1
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Sujet
- VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells.Synonyms: INCAM-100, L1CAM, V-CAM 1, VCAM-1, Vascular cell adhesion protein 1
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ID gène
- 7412
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NCBI Accession
- NP_001069
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UniProt
- P19320
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Pathways
- Carbohydrate Homeostasis
Antigène
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