P-Selectin anticorps

N° du produit ABIN320269

Détail du produit anti-P-Selectin anticorps

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivité: Humain, Rat, Mouton, Chévre

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Selectin est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: SM2262P recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-selectin. Clone Psel.KO.2.12 is reported to inhibit P-Selectin-dependent adhesion between HL60 cells and P-Selectin transfected COS cells (1). We recommend the use of SM2262LE for this purpose.

Purification: Affinity Chromatography on Protein G

Immunogène: CD62P transfected 300.19 cells. Remarks: Spleen cells from immunised CD62P knock-out mice (Strain C57/B6) were fused with cells of the NS-1 myeloma cell line.

Clone: Psel-KO-2-12

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 106 cells in 100 μL. Immunohistology on Frozen Sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur P-Selectin

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Autre désignation: CD62P / P-Selectin (SELP Produits)

Synonymes: anticorps PSELECT, anticorps CD62, anticorps CD62P, anticorps GMP140, anticorps GRMP, anticorps LECAM3, anticorps PADGEM, anticorps PSEL, anticorps GMP-140, anticorps Grmp, anticorps selectin P, anticorps selectin, platelet, anticorps Selp, anticorps SELP

Sujet: CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

ID gène: 6403

NCBI Accession: NP_002996

UniProt: P16109