Estrogen Receptor alpha anticorps (Estrogen Receptor 1) (AA 410-592)

Details for Product anti-ESR1 Antibody No. ABIN3210000
Antigène
Épitope
AA 410-592
69
53
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25
23
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Reactivité
Humain
974
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1
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Hôte
Souris
730
291
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Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp Estrogen Receptor alpha est non-conjugé
47
30
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Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
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Options
Immunogène ER alpha antibody was raised in Mouse using a purified recombinant fragment of human ER-alpha (410-592 aa) expressed in E. coli as the immunogen.
Clone 2B7
Isotype IgG1
Purification Purified antibody.
Antigène
Autre désignation ER alpha (ESR1 Antibody Extrait)
Sujet The estrogen receptor (ESR) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less variability. Synonyms: Monoclonal ER alpha antibody, Anti-ER alpha antibody, Estrogen receptor alpha antibody, ERA antibody, NR3A1 antibody.
Pathways Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Indications d'application ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.
Restrictions For Research Use only
Concentration Lot specific
Buffer Purified antibody supplied in PBS containing 0.03 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
Stock RT/-20 °C
Stockage commentaire Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Images (Fournisseur)
Image no. 1 for anti-Estrogen Receptor 1 (ESR1) (AA 410-592) antibody (ABIN3210000) Western Blot showing ER-alpha antibody used against human breast carcinoma tissue lys...
Image no. 2 for anti-Estrogen Receptor 1 (ESR1) (AA 410-592) antibody (ABIN3210000) Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using ER-al...