BACE1 anticorps
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- Antigène Voir toutes BACE1 Anticorps
- BACE1 (Beta-secretase 1 (BACE1))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BACE1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Neutralization (Neut)
- Specificité
- Recognizes human BACE-1 ectodomain. Species cross-reactivity: Mouse.
- Purification
- Protein G purified
- Immunogène
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NS0-derived rhBACE-1 ectodomain.
Type of Immunogen: Recombinant protein - Isotype
- IgG1
- Top Product
- Discover our top product BACE1 Anticorps primaire
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- Indications d'application
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Approved: ELISA, IP, Neut, WB
Usage: Suitable for use in ELISA, Immunoprecipitation/ Western Blot and Neutralization. The enzyme was then assayed with a peptide substrate. 50 % of the proteolytic activity was inhibited by the antibody at 10 μg/mL (IC50) under conditions in which the enzyme was present at 10 μg/mL and the substrate concentration was 10uM. Considering the molecular masses of the enzyme (75kD) and the antibody (150kD), IC50 was achieved at ~0.5:1 Molar ratio of the antibody to the enzyme. Did not inhibit rhCathepsin D activity under the same conditions. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Sterile PBS
- Concentration
- Lot specific
- Buffer
- Lyophilized, PBS, pH 7.4, 5 % trehalose
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Antigène
- BACE1 (Beta-secretase 1 (BACE1))
- Autre désignation
- BACE1 / BACE (BACE1 Produits)
- Synonymes
- anticorps ASP2, anticorps BACE, anticorps HSPC104, anticorps C76936, anticorps Bace, anticorps MGC145931, anticorps BACE1, anticorps zgc:77409, anticorps beta-secretase 1, anticorps beta-site APP cleaving enzyme 1, anticorps beta-site APP-cleaving enzyme 1, anticorps BACE1, anticorps Bace1, anticorps bace1
- Sujet
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Name/Gene ID: BACE1
Subfamily: Aspartic A1
Family: Protease
Synonyms: BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2 - ID gène
- 23621
- UniProt
- P56817
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