Desmin anticorps (C-Term)

N° du produit ABIN334386

Cet anticorps anti-Desmin est un anticorps Chèvre Polyclonal détectant Desmin dans WB, IHC et ELISA. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour Desmin anticorps (C-Term) (ABIN334386)

Antigène: Desmin (DES)

Reactivité: Humain, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Classe de qualité: Verified

Détail du produit anti-Desmin anticorps

Épitope: C-Term

Fonction: Desmin

Séquence: RDGEVVSEAT QQQHE

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-RDGEVVSEATQQQHE, from the C Terminus of the protein sequence according to NP_001918.3.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry: Paraffin embedded Human Heart. Recommended concentration: 4-6 μg/mL.

Western Blot: Approx. 55-60 kDa band observed in Human and Mouse Skeletal Muscle lysates and in Human Heart lysates (calculated MW of 53.5 kDa according to Human NP_001918.3, and Mouse NP_034173.1). Preliminary testing showed a band at approx 60 kDa in Rat

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Références pour anticorps anti-Desmin (ABIN334386)

Kreutz, Gaab, Dona, Pinto, Tallquist, Groneberg, Friebe: "Analysis of cellular NO-GC expression in the murine heart and lineage determination in angiotensin II-induced fibrosis." dans: iScience, Vol. 28, Issue 1, pp. 111615, (2025) (PubMed).

Aue, Englert, Harrer, Schwiering, Gaab, König, Adams, Schmidtko, Friebe, Groneberg: "NO-sensitive guanylyl cyclase discriminates pericyte-derived interstitial from intra-alveolar myofibroblasts in murine pulmonary fibrosis." dans: Respiratory research, Vol. 24, Issue 1, pp. 167, (2023) (PubMed).

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: DES

Sujet: DES, desmin, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, intermediate filament protein

ID gène: 1674, 13346, 64362

NCBI Accession: NP_001918