BID anticorps (N-Term)
Aperçu rapide pour BID anticorps (N-Term) (ABIN336094)
Antigène
Voir toutes BID AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-195, N-Term
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Specificité
- The antibody recognizes human BID. Other species not tested.
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Attributs du produit
- Synonyms: p22 BID, BH3-interacting domain death agonist
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Purification
- Protein-G affinity chromatography
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Immunogène
- Recombinant human BID (aa 1-195) purified from E. coli
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Isotype
- IgG1
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Indications d'application
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ELISA. Western blot (1,000 - 2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- BID (BH3 Interacting Domain Death Agonist (BID))
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Autre désignation
- BID
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Sujet
- BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases.Synonyms: BH3-interacting domain death agonist, p22 BID
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ID gène
- 637
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UniProt
- P55957
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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