TPSAB1 anticorps

N° du produit ABIN337075

Cet anticorps Souris Monoclonal détecte spécifiquement TPSAB1 dans WB, IHC, ELISA, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain, Rat, Chien, Cat et Singe.

Aperçu rapide pour TPSAB1 anticorps (ABIN337075)

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Reactivité: Humain, Rat, Chien, Cat, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TPSAB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: AA1

Détail du produit anti-TPSAB1 anticorps

Specificité: Recognizes human mast cell tryptase, both isoforms. Is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology. Tryptases are the products of a number of and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction.

Purification: Protein G purified

Immunogène: Human mast cell tryptase purified from human lung tissue.

Type of Immunogen: Purified protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, IHC, IHC-Fr, IHC-P (2.5 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL. Histology Positive Control Tissue: Tonsil.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.

Détails sur TPSAB1

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Autre désignation: TPSAB1 / Mast Cell Tryptase

Sujet: Name/Gene ID: TPSAB1
Subfamily: Serine S1
Family: Protease

Synonyms: TPSAB1, Alpha tryptase, Mast cell alpha II tryptase, Tryptase alpha-1, Tryptase beta I, Tryptase-III, TPSB1, Tryptase alpha II, TPS1, TPS2, Tryptase beta-1, Tryptase-1, Tryptase-I, Mast cell beta I tryptase, Tryptase alpha/beta 1, Tryptase alpha/beta-1, Tryptase beta 1, Tryptase I

ID gène: 7177

UniProt: Q15661