Progesterone Receptor anticorps (C-Term)

N° du produit ABIN342255

Cet anticorps anti-Progesterone Receptor est un anticorps Souris Monoclonal détectant Progesterone Receptor dans WB. Adapté pour Humain.

Aperçu rapide pour Progesterone Receptor anticorps (C-Term) (ABIN342255)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Progesterone Receptor anticorps

Épitope: C-Term

Specificité: Recognizes human progesterone receptor (PgR), a member of the steroid family of nuclear receptors. PgR is found as a 94 kD protein (Form A) or a 120 kD protein (Form B). Binding of progesterone to its receptor results in a conformational change that allows dimerization and binding of the receptor to progesterone response elements and activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription.

Purification: Protein G purified

Immunogène: 6-His fusion protein containing the region encoding aa 1-101 of human progesterone receptor expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG2a

Information d'application

Indications d'application: Approved: WB (1 - 5 μg/mL)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Conseil sur la manipulation: Avoid freeze/thaw cycles.

Stock: -80 °C

Stockage commentaire: Store at -70°C, avoid freeze/thaw cycles.

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: PGR/PR/Progesterone Receptor

Sujet: Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: PGR, NR3C3, PR, Progesterone receptor

ID gène: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration