Ubinuclein 1 anticorps (AA 1-190)

N° du produit ABIN343714

Cet anticorps Souris Monoclonal détecte spécifiquement Ubinuclein 1 dans WB et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour Ubinuclein 1 anticorps (AA 1-190) (ABIN343714)

Antigène: Ubinuclein 1 (UBN1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ubinuclein 1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: UBN1-02

Détail du produit anti-Ubinuclein 1 anticorps

Épitope: AA 1-190

Fonction: Anti-UBN1 Purified

Specificité: The antibody UBN1-02 recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

Réactivité croisée (Details): Human, Other species Not tested

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Western blotting: Recommended dilution: 1-5 μg/mL, positive control: HeLa cell line.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur Ubinuclein 1

Antigène: Ubinuclein 1 (UBN1)

Autre désignation: UBN1

Sujet: Ubinuclein 1,Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.,Ubinuclein 1, VT4

ID gène: 29855

UniProt: Q6PIZ9