TTC3 anticorps (N-Term)

N° du produit ABIN347721

Détail du produit anti-TTC3 anticorps

Antigène: TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTC3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Specificité: Reacts with human E3 ubiquitin-protein ligase TTC3

Purification: Antiserum

Immunogène: Synthetic peptide derived from Cter domain of human TTC3

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:100 - 1:500) WB(1:500 - 1:5000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur TTC3

Antigène: TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))

Autre désignation: E3 ubiquitin-protein ligase TTC3 (TTC3 Produits)

Synonymes: anticorps DCRR1, anticorps RNF105, anticorps TPRDIII, anticorps 2610202A04Rik, anticorps AA409221, anticorps D16Ium21, anticorps D16Ium21e, anticorps TPRD, anticorps mKIAA4119, anticorps TTC3, anticorps tetratricopeptide repeat domain 3, anticorps E3 ubiquitin-protein ligase TTC3, anticorps TTC3, anticorps Ttc3, anticorps LOC100562480

Sujet: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

UniProt: P53804