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TTC3 anticorps (AA 251-350)

TTC3 Reactivité: Souris, Rat IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6989022
  • Antigène Voir toutes TTC3 Anticorps
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Épitope
    • 2
    • 2
    • 1
    • 1
    AA 251-350
    Reactivité
    • 5
    • 3
    • 2
    Souris, Rat
    Hôte
    • 5
    • 2
    Lapin
    Clonalité
    • 6
    • 1
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    Cet anticorp TTC3 est non-conjugé
    Application
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RNF105
    Isotype
    IgG
    Top Product
    Discover our top product TTC3 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Autre désignation
    RNF105 (TTC3 Produits)
    Synonymes
    anticorps DCRR1, anticorps RNF105, anticorps TPRDIII, anticorps 2610202A04Rik, anticorps AA409221, anticorps D16Ium21, anticorps D16Ium21e, anticorps TPRD, anticorps mKIAA4119, anticorps TTC3, anticorps tetratricopeptide repeat domain 3, anticorps E3 ubiquitin-protein ligase TTC3, anticorps TTC3, anticorps Ttc3, anticorps LOC100562480
    Sujet

    Synonyms: DCRR1, E3 ubiquitin protein ligase TTC3, E3 ubiquitin-protein ligase TTC3, Protein DCRR1, RING finger protein 105,Tetratricopeptide repeat protein 3 (TPR repeat protein D), Tetratricopeptide repeat protein 3, TPR repeat protein 3, TPR repeat protein D, TPRD, TPRDI, TPRDII, TPRDIII, TTC3, TTC3_HUMAN.

    Background: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

    ID gène
    7267
    UniProt
    P53804
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