CHMP3 anticorps (N-Term)

N° du produit ABIN350228

L’anticorps Mouton Polyclonal anti-CHMP3 a été validé pour WB et IHC. Il convient pour détecter CHMP3 dans des échantillons de Humain.

Aperçu rapide pour CHMP3 anticorps (N-Term) (ABIN350228)

Antigène: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CHMP3 anticorps

Épitope: N-Term

Fonction: Sheep antibody to CHMP3

Specificité: Specific for CHMP3.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the n-terminal of human CHMP3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur CHMP3

Antigène: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Autre désignation: CHMP3

Sujet: FUNCTION: Component of the ESCRT-III complex which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. Required for sorting/trafficking of EGF receptor. In case of infection the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins. SUBCELLULAR LOCATION: Cytoplasm cytosol. Membrane, Lipid-anchor. TISSUE SPECIFICITY: Widely expressed. Expressed in heart brain placenta lung liver skeletal muscle kidney and pancreas.

UniProt: Q9Y3E7