VPS36 anticorps (Internal Region)

N° du produit ABIN351331

Cet anticorps Lapin Polyclonal détecte spécifiquement VPS36 dans IHC et WB. Il présente une réactivité envers Souris.

Aperçu rapide pour VPS36 anticorps (Internal Region) (ABIN351331)

Antigène: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS36 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-VPS36 anticorps

Épitope: Internal Region

Fonction: Rabbit antibody to VPS36

Specificité: Specific for VPS36.

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the internal region of mouse VPS36 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur VPS36

Antigène: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Autre désignation: VPS36

Sujet: FUNCTION: Component of the ESCRT-II complex which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation possibly via its interaction with ELL. SUBCELLULAR LOCATION: Cytoplasm. Late endosome. Nucleus. NoteL Colocalizes with ubiquitinated proteins on late endosomes.

UniProt: Q91XD6