Fibrillin 1 anticorps (Biotin)

N° du produit ABIN356181

Cet anticorps anti-Fibrillin 1 est un anticorps Souris Monoclonal détectant Fibrillin 1 dans WB, IHC (fro), IF et IEM. Adapté pour Humain et Boeuf (Vache).

Aperçu rapide pour Fibrillin 1 anticorps (Biotin) (ABIN356181)

Antigène: Fibrillin 1 (FBN1)

Reactivité: Humain, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibrillin 1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunoelectron Microscopy (IEM)

Clone: 11C1-3

Détail du produit anti-Fibrillin 1 anticorps (Biotin)

Specificité: This antibody recognises Fibrillin (Mr 350 kDa).

Attributs du produit: Synonyms: FBN1, FBN

Immunogène: Microfibrils from zonular apparatus of bovine eye.

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry: 1/50-1/100 (30-60 min at RT). (See Ref.2)Immunofluorescence. (See Ref.2)Western Blotting: < / = 1 μg/mL. Electron microscopic Immunolocalization.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Fibrillin 1

Antigène: Fibrillin 1 (FBN1)

Autre désignation: Fibrillin-1

Sujet: The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.(Ref.1) In Immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues.(Ref.2,3) There is an aberrant expression of fibrillin in Marfan syndrome.(Ref.4)Synonyms: FBN, FBN1

ID gène: 2200

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome