Fibrillin 1 anticorps

N° du produit ABIN356183

L’anticorps anti-Fibrillin 1 Monoclonal Souris est utilisé pour la détection de Fibrillin 1 dans des échantillons de Humain et Boeuf (Vache). Il a été validé pour WB, IHC (fro), IF et EM.

Aperçu rapide pour Fibrillin 1 anticorps (ABIN356183)

Antigène: Fibrillin 1 (FBN1)

Reactivité: Humain, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibrillin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Electron Microscopy (EM)

Clone: 11C1-3

Détail du produit anti-Fibrillin 1 anticorps

Specificité: This antibody recognises Fibrillin (Mr 350 kDa).

Attributs du produit: Synonyms: FBN1, FBN

Purification: Purified

Immunogène: Microfibrils from zonular apparatus of bovine eye.

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry: 1/50-1/100 (30-60 min at RT). (See Ref.2)Immunofluorescence. (See Ref.2)Western blotting: < / = 1 μg/mL (See Ref.2)Electron Microscopic Immunolocalization. (See Ref.2)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur Fibrillin 1

Antigène: Fibrillin 1 (FBN1)

Autre désignation: Fibrillin-1

Sujet: The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.(Ref.1) In Immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues.(Ref.2,3) There is an aberrant expression of fibrillin in Marfan syndrome.(Ref.4)Synonyms: FBN, FBN1

ID gène: 2200

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome