Cet anticorps anti-PINK1 Monoclonal Souris (Clone 38CT18-7) (ABIN356391) détecte spécifiquement PINK1 dans WB et IHC (p).
L’anticorps est réactif avec des échantillons de Humain et Souris.
ELISA: 1/1,000. Western blotting: 1/500-1/2000. Immunohistochemistry: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Date de péremption
12 months
Antigène
PINK1
(PTEN Induced Putative Kinase 1 (PINK1))
Autre désignation
PINK1
Sujet
Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.Synonyms: BRPK, PARK6, PINK-1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6, Serine/threonine-protein kinase PINK1, mitochondrial