Thyroglobulin anticorps

N° du produit ABIN356463

Cet anticorps anti-Thyroglobulin est un anticorps Lapin Polyclonal détectant Thyroglobulin dans IHC (p), IF et IHC (fro). Adapté pour Humain.

Aperçu rapide pour Thyroglobulin anticorps (ABIN356463)

Antigène: Thyroglobulin (TG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thyroglobulin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Thyroglobulin anticorps

Specificité: This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of Tg in metastatic lesion establishes thyroid origin of tumor.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogène: Purified human Thyroglobulin.

Isotype: IgG

Information d'application

Indications d'application: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100 using streptavidinapprox. biotin system orpolymer system. Immunofluorescence. Recommended Positive Control: Human thyroid.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Thyroglobulin

Antigène: Thyroglobulin (TG)

Sujet: Thyroglobulin (Tg) is a 660 kDa dimeric protein produced by and used by entirely within thyroid gland. Tg is used by the thyroid gland to produce the thyroid hormone thyroxine (T4) and triiodothyronine (T3). Tg is produced by the thyroid epithelial cells, called thyrocytes, which form spherical follicles. Tg is stored in the follicle lumen. Tg levels in the blood can be used as markers for certain kind of thyroid cancer. Tg levels are also elevated in Graves disease.Synonyms: TGN, Thyreoglobulin

ID gène: 7038

NCBI Accession: NP_003226

UniProt: P01266

Pathways: Thyroid Hormone Synthesis