Caspase 6 anticorps (C-Term)
Aperçu rapide pour Caspase 6 anticorps (C-Term) (ABIN356823)
Antigène
Voir toutes Caspase 6 (CASP6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody is specific to Caspase-6 (C-term).
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Purification
- Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CASP6.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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Autre désignation
- Caspase-6
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Sujet
- CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
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ID gène
- 839, 9606
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UniProt
- P55212
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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