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Cadherin 8 anticorps (N-Term)

CDH8 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN356866
  • Antigène Voir toutes Cadherin 8 (CDH8) Anticorps
    Cadherin 8 (CDH8)
    Épitope
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 39
    • 17
    • 17
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Humain
    Hôte
    • 38
    • 1
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cadherin 8 est non-conjugé
    Application
    • 27
    • 23
    • 19
    • 7
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody is specific to CDH8 (N-term).
    Purification
    Protein A Chromatography followed by Peptide Affinity purification.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CDH8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CDH8 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Kher, Sha, Escobar, Andreoli, Wang, Xu, Wandinger-Ness, Bacallao: "Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture." dans: American journal of physiology. Cell physiology, Vol. 301, Issue 1, pp. C99-C105, (2011) (PubMed).

  • Antigène
    Cadherin 8 (CDH8)
    Autre désignation
    Cadherin-8 (CDH8 Produits)
    Synonymes
    anticorps AI851472, anticorps cad8, anticorps cadherin-8, anticorps Nbla04261, anticorps cadherin 8, anticorps cadherin 8, type 2, anticorps Cdh8, anticorps CDH8
    Sujet
    CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.Synonyms: CDH8
    ID gène
    1006, 9606
    UniProt
    P55286
    Pathways
    Cell-Cell Junction Organization
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