TLR7 anticorps (N-Term)
Aperçu rapide pour TLR7 anticorps (N-Term) (ABIN357057)
Antigène
Voir toutes TLR7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects TLR7 at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human and Mouse.
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Purification
- Protein Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human TLR7.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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Autre désignation
- TLR7
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Sujet
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.Synonyms: Toll-like receptor 7
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Poids moléculaire
- 120921 Da
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ID gène
- 51284, 9606
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UniProt
- Q9NYK1
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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