GJA3 anticorps (N-Term)
Aperçu rapide pour GJA3 anticorps (N-Term) (ABIN357087)
Antigène
Voir toutes GJA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects GJA3 at N-term.
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Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human GJA3.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))
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Autre désignation
- GJA3 / Cx46
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Sujet
- GJA3, an integral membrane protein, belong to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and nonjunctional ('hemi-') channels. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3), a form of autosomal dominant congenital cataract.Synonyms: Connexin-46, Gap junction alpha-3 protein
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Poids moléculaire
- 47296 Da
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ID gène
- 2700, 9606
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UniProt
- Q9Y6H8
Antigène
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