GJC1 anticorps (N-Term)
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- Antigène Voir toutes GJC1 Anticorps
- GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GJC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects GJA7 at N-term.
- Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GJA7.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GJC1 Anticorps primaire
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- Indications d'application
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ELISA 1: 1,000. Western blotting 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))
- Autre désignation
- GJC1 / Cx45 (GJC1 Produits)
- Synonymes
- anticorps CX45, anticorps GJA7, anticorps cx45, anticorps gja7, anticorps MGC52735, anticorps GJD3, anticorps GJC1, anticorps C130009G16Rik, anticorps Cnx45, anticorps Cx45, anticorps Gja-7, anticorps Gja7, anticorps gap junction protein gamma 1, anticorps gap junction protein gamma 1 L homeolog, anticorps gap junction protein, delta 3, 31.9kDa, anticorps gap junction protein, gamma 1, anticorps Gap junction gamma-1 protein, anticorps GJC1, anticorps gjc1.L, anticorps GJD3, anticorps Gjc1, anticorps gjc1
- Sujet
- Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.Synonyms: Connexin-45, GJA7, Gap junction alpha-7 protein, Gap junction gamma-1 protein
- ID gène
- 10052, 9606
- UniProt
- P36383
- Pathways
- Cell-Cell Junction Organization
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