SIGLEC5 anticorps (N-Term)

N° du produit ABIN357143

Détail du produit anti-SIGLEC5 anticorps

Antigène: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGLEC5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Thisa ntibody detects SIGLEC5 at N-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SIGLEC5.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur SIGLEC5

Antigène: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Autre désignation: CD170 / SIGLEC5 (SIGLEC5 Produits)

Synonymes: anticorps CD170, anticorps CD33L2, anticorps OB-BP2, anticorps OBBP2, anticorps SIGLEC-5, anticorps sialic acid binding Ig like lectin 5, anticorps sialic acid-binding Ig-like lectin 5, anticorps sialic acid binding Ig-like lectin 5, anticorps SIGLEC5, anticorps LOC100597560, anticorps Siglec5

Sujet: SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation.Synonyms: CD33 antigen-like 2, CD33L2, OB-binding protein 2, OBBP2, Obesity-binding protein 2, Sialic acid-binding Ig-like lectin 5, Siglec-5

Poids moléculaire: 60715 Da

ID gène: 8778, 5874

UniProt: O15389