UBE4B anticorps (N-Term)
Aperçu rapide pour UBE4B anticorps (N-Term) (ABIN357483)
Antigène
Voir toutes UBE4B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Specificité
- This antibody detects UBE4B at N-term.
-
Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
-
Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBE4B.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
-
ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
-
- UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))
-
Autre désignation
- UBE4B
-
Sujet
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.Synonyms: HDNB1, Homozygously deleted in neuroblastoma 1, KIAA0684, UFD2, Ubiquitin conjugation factor E4 B, Ubiquitin fusion degradation protein 2
-
Poids moléculaire
- 133275 Da
-
ID gène
- 10277, 9606
-
UniProt
- O95155
Antigène
-