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USP14 anticorps (N-Term)

USP14 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357546
  • Antigène Voir toutes USP14 Anticorps
    USP14 (Ubiquitin Specific Peptidase 14 (USP14))
    Épitope
    • 13
    • 12
    • 9
    • 8
    • 8
    • 2
    • 2
    • 1
    N-Term
    Reactivité
    • 68
    • 9
    • 8
    • 5
    • 2
    • 1
    Humain
    Hôte
    • 58
    • 9
    Lapin
    Clonalité
    • 52
    • 16
    Polyclonal
    Conjugué
    • 31
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp USP14 est non-conjugé
    Application
    • 50
    • 34
    • 18
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody is specific to USP14 (N-term). Predicted to cross react with Mouse (100 % Antigen Homology).
    Purification
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human USP14.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP14 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    USP14 (Ubiquitin Specific Peptidase 14 (USP14))
    Autre désignation
    USP14 (USP14 Produits)
    Synonymes
    anticorps TGT, anticorps DDBDRAFT_0202821, anticorps DDBDRAFT_0237695, anticorps DDB_0202821, anticorps DDB_0237695, anticorps 2610005K12Rik, anticorps 2610037B11Rik, anticorps AW107924, anticorps C78769, anticorps ax, anticorps zgc:55949, anticorps wu:fk63d09, anticorps MGC81945, anticorps tgt, anticorps MGC69343, anticorps USP14, anticorps ubiquitin specific peptidase 14, anticorps peptidase C19 family protein, anticorps ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase), anticorps ubiquitin specific protease 14, anticorps ubiquitin specific peptidase 14 S homeolog, anticorps universal stress protein, anticorps Ubiquitin carboxyl-terminal hydrolase 14, anticorps USP14, anticorps usp14, anticorps Usp14, anticorps Bm1_28765, anticorps usp14.S, anticorps RR_RS06480, anticorps usp-14
    Sujet
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 14, TGT, Ubiquitin carboxyl-terminal hydrolase 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14
    Poids moléculaire
    55938 Da
    ID gène
    9097, 5874
    UniProt
    P54578
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