HSF1 anticorps (Sumoylation Site)

N° du produit ABIN357730

Détail du produit anti-HSF1 anticorps

Antigène: HSF1 (Heat Shock Factor Protein 1 (HSF1))

Épitope: Sumoylation Site

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSF1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects HSF1 Sumoylation Site.

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with the KLH conjugated synthetic peptide PLVRVKEEPPSPPQSPR containing a predicted sumoylation site from the central region of human HSF1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur HSF1

Antigène: HSF1 (Heat Shock Factor Protein 1 (HSF1))

Autre désignation: Heat Shock Factor 1 / HSF1 (HSF1 Produits)

Synonymes: anticorps hsf1, anticorps Hsf, anticorps xhsf1, anticorps AA960185, anticorps HSTF1, anticorps HSF1, anticorps HSF, anticorps HSF1c, anticorps hsf1a, anticorps hsf1b, anticorps zHSF1a, anticorps zHSF1b, anticorps hstf1, anticorps heat shock factor, anticorps Heat Shock Factor, anticorps heat shock factor 1, anticorps heat shock transcription factor 1, anticorps heat shock transcription factor 1 S homeolog, anticorps hsf1, anticorps hsf-1, anticorps Hsf1, anticorps HSF1, anticorps hsf1.S

Sujet: Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.Synonyms: HSF-1, HSTF1, Heat shock transcription factor 1

Poids moléculaire: 57260 Da

ID gène: 3297, 9606

UniProt: Q00613