MARCKS anticorps (C-Term)
Aperçu rapide pour MARCKS anticorps (C-Term) (ABIN357762)
Antigène
Voir toutes MARCKS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 247-276, C-Term
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Specificité
- This antibody is specific to Human MARCKS (C-term).
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Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- KLH conjugated synthetic peptide between 247~276 amino acids from the C-terminal region of human MARCKS
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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Autre désignation
- MARCKS
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Sujet
- MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.Synonyms: MACS, Myristoylated alanine-rich C-kinase substrate, PRKCSL
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Poids moléculaire
- 31413 Da
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ID gène
- 4082
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NCBI Accession
- NP_002347
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UniProt
- P29966
Antigène
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