ERVW-1 anticorps (Middle Region)
Aperçu rapide pour ERVW-1 anticorps (Middle Region) (ABIN357849)
Antigène
Voir toutes ERVW-1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- This antibody detects ERVWE1 (Center).
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Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ERVWE1.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))
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Autre désignation
- ERVWE1
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Sujet
- Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.Synonyms: Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W_7q21.2 provirus ancestral Env polyprotein, Syncytin, Syncytin-1
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Poids moléculaire
- 59866 Da
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ID gène
- 30816, 9606
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UniProt
- Q9UQF0
Antigène
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