Cadherin 5 anticorps (N-Term)

N° du produit ABIN357862

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin 5 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Cadherin 5 anticorps (N-Term) (ABIN357862)

Antigène: Cadherin 5 (CDH5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Cadherin 5 anticorps

Épitope: N-Term

Specificité: This antibody detects VE Cadherin (CD144/CDH5) (N-term).

Purification: Protein A Chromatography followed by peptide affinity purification

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the N-term of human CDH5.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: CD144 / Cadherin-5

Sujet: CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.Synonyms: 7B4 antigen, CDH5, VE-Cadherin, Vascular endothelial cadherin

Poids moléculaire: 87516 Da

ID gène: 1003, 9606

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2