CD131 anticorps (pTyr766)
Aperçu rapide pour CD131 anticorps (pTyr766) (ABIN358147)
Antigène
Voir toutes CD131 (CSF2RB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr766
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Specificité
- This antibody detects IL3R pTyr766.
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Purification
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y766 of human IL3R.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Dot Blot: 1/500. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))
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Autre désignation
- CD131 / CSF2RB
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Sujet
- IL3R (also known as CSF2RB) is a common beta chain of the high affinity receptor for IL-3, IL-5 and GM-CSF. Defective IL3R has been reported to be associated with protein alveolar proteinosis (PAP). PAP is an autosomal recessive fatal respiratory disease.Synonyms: Cytokine receptor common subunit beta, GM-CSF-RB, GM-CSF/IL-3/IL-5 receptor common beta-chain, IL3RB, IL5RB
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Poids moléculaire
- 97336 Da
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ID gène
- 1439, 9606
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UniProt
- P32927
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Pathways
- Signalistation JAK/STAT
Antigène
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