MMP24 anticorps (Middle Region)

N° du produit ABIN358694

L’anticorps Lapin Polyclonal anti-MMP24 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter MMP24 dans des échantillons de Humain.

Aperçu rapide pour MMP24 anticorps (Middle Region) (ABIN358694)

Antigène: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP24 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-MMP24 anticorps

Épitope: Middle Region

Specificité: This antibody reacts top MMP24.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MMP24.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MMP24

Antigène: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Autre désignation: MMP-24

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP24 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed matrix metalloproteinase 24 (MMP24).Synonyms: MMP24, MT-MMP 5, MT5-MMP, MT5MMP, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5

ID gène: 10893, 5874

UniProt: Q9Y5R2