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MMP25 anticorps (C-Term)

Cet anticorps anti-MMP25 est un anticorps Lapin Polyclonal détectant MMP25 dans WB et EIA. Adapté pour Humain et Souris.
N° du produit ABIN358695

Aperçu rapide pour MMP25 anticorps (C-Term) (ABIN358695)

Antigène

Voir toutes MMP25 Anticorps
MMP25 (Matrix Metallopeptidase 25 (MMP25))

Reactivité

  • 35
  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 31
  • 4
Lapin

Clonalité

  • 31
  • 4
Polyclonal

Conjugué

  • 16
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp MMP25 est non-conjugé

Application

  • 21
  • 11
  • 9
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    This antibody reacts to MMP25.

    Purification

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogène

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MMP25.

    Isotype

    Ig Fraction
  • Indications d'application

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène

    MMP25 (Matrix Metallopeptidase 25 (MMP25))

    Autre désignation

    MMP-25

    Sujet

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).Synonyms: Leukolysin, MMP20, MMP25, MMPL1, MT-MMP 6, MT6-MMP, MT6MMP, Matrix metalloproteinase-25, Membrane-type matrix metalloproteinase 6

    ID gène

    64386, 5874

    UniProt

    Q9NPA2
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