MMP25 anticorps (C-Term)
Aperçu rapide pour MMP25 anticorps (C-Term) (ABIN358695)
Antigène
Voir toutes MMP25 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- This antibody reacts to MMP25.
-
Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
-
Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MMP25.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
-
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- MMP25 (Matrix Metallopeptidase 25 (MMP25))
-
Autre désignation
- MMP-25
-
Sujet
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).Synonyms: Leukolysin, MMP20, MMP25, MMPL1, MT-MMP 6, MT6-MMP, MT6MMP, Matrix metalloproteinase-25, Membrane-type matrix metalloproteinase 6
-
ID gène
- 64386, 5874
-
UniProt
- Q9NPA2
Antigène
-