MMP25 anticorps (C-Term)

N° du produit ABIN358695

Détail du produit anti-MMP25 anticorps

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP25 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to MMP25.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MMP25.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MMP25

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Autre désignation: MMP-25 (MMP25 Produits)

Synonymes: anticorps MMP-25, anticorps MMP20, anticorps MMP20A, anticorps MMPL1, anticorps MT-MMP 6, anticorps MT-MMP6, anticorps MT6-MMP, anticorps MT6MMP, anticorps MTMMP6, anticorps F730048C11Rik, anticorps Leukolysin, anticorps matrix metallopeptidase 25, anticorps MMP25, anticorps Mmp25

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).Synonyms: Leukolysin, MMP20, MMP25, MMPL1, MT-MMP 6, MT6-MMP, MT6MMP, Matrix metalloproteinase-25, Membrane-type matrix metalloproteinase 6

ID gène: 64386, 5874

UniProt: Q9NPA2