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Sclerostin anticorps (Middle Region)

SOST Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN358752
  • Antigène Voir toutes Sclerostin (SOST) Anticorps
    Sclerostin (SOST)
    Épitope
    • 15
    • 11
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 141-171, Middle Region
    Reactivité
    • 69
    • 52
    • 35
    • 16
    • 15
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 71
    • 3
    • 2
    • 1
    Lapin
    Clonalité
    • 72
    • 5
    Polyclonal
    Conjugué
    • 29
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp Sclerostin est non-conjugé
    Application
    • 74
    • 35
    • 28
    • 24
    • 13
    • 11
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes SOST (Center).
    Purification
    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    KLH conjugated synthetic peptide between 141~171 amino acids from the Center region of Human SOST.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SOST Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western Blot: 1/50-1/100Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    Sclerostin (SOST)
    Autre désignation
    Sclerostin / SOST (SOST Produits)
    Synonymes
    anticorps LOC100313724, anticorps CDD, anticorps VBCH, anticorps 5430411E23Rik, anticorps sclerostin, anticorps LOC100313724, anticorps SOST, anticorps Sost
    Sujet
    Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
    ID gène
    50964, 9606
    UniProt
    Q9BQB4
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