ZBTB7B anticorps (Middle Region)

N° du produit ABIN358973

L’anticorps Lapin Polyclonal anti-ZBTB7B a été validé pour WB, IHC (p) et EIA. Il convient pour détecter ZBTB7B dans des échantillons de Humain et Souris.

Aperçu rapide pour ZBTB7B anticorps (Middle Region) (ABIN358973)

Antigène: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB7B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ZBTB7B anticorps

Épitope: Middle Region

Specificité: This antibody reacts to ZBTB7B.

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZBTB7B.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur ZBTB7B

Antigène: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Autre désignation: ZBTB7B

Sujet: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.Synonyms: T-helper-inducing POZ/Krueppel-like factor, Th-POK, Thpok, ZBT-15, ZBTB15, ZFP67, Zfp-67, Zinc finger and BTB domain-containing protein 15, Zinc finger and BTB domain-containing protein 7B, Zinc finger protein 67 homolog, c-Krox, cKrox

ID gène: 51043, 9606

UniProt: O15156