ZBTB7B anticorps (C-Term)

N° du produit ABIN1882155

Détail du produit anti-ZBTB7B anticorps

Antigène: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Épitope: AA 440-469, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB7B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-469 amino acids from the C-terminal region of human ZBTB7B.

Clone: RB13260

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ZBTB7B (ABIN1882155)

Matsumoto, Nagoshi, Yoshida, Kato, Kuroda, Shimura, Kaneko, Horiike, Nakamura, Taniwaki: "Expression of Master Regulators of T-cell, Helper T-cell and Follicular Helper T-cell Differentiation in Angioimmunoblastic T-cell Lymphoma." dans: Internal medicine (Tokyo, Japan), Vol. 56, Issue 21, pp. 2851-2856, (2018) (PubMed).

Matsumoto, Horiike, Ohshiro, Yamamoto, Sasaki, Tsutsumi, Kobayashi, Shimizu, Uchiyama, Kuroda, Nomura, Shimazaki, Taniwaki: "Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis." dans: American journal of clinical pathology, Vol. 133, Issue 2, pp. 281-90, (2010) (PubMed).

Galéra, Musso, Ducy, Karsenty: "c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 20, pp. 9372-6, (1994) (PubMed).

Détails sur ZBTB7B

Antigène: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Autre désignation: ZBTB7B (ZBTB7B Produits)

Synonymes: anticorps THPOK, anticorps ZBTB15, anticorps ZFP-67, anticorps ZFP67, anticorps ZNF857B, anticorps c-KROX, anticorps hcKROX, anticorps Thpok, anticorps Zfp67, anticorps c-Krox, anticorps ZBTB7B, anticorps zbtb7b, anticorps MGC130914, anticorps zinc finger and BTB domain containing 7B, anticorps kruppel-related zinc finger protein hcKrox, anticorps ZBTB7B, anticorps Zbtb7b, anticorps zbtb7b

Sujet: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Poids moléculaire: 58027

NCBI Accession: NP_001239335, NP_001243384

UniProt: O15156