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PINK1 anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-PINK1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter PINK1 dans des échantillons de Humain.
N° du produit ABIN358994

Aperçu rapide pour PINK1 anticorps (N-Term) (ABIN358994)

Antigène

Voir toutes PINK1 Anticorps
PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reactivité

  • 82
  • 28
  • 10
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 55
  • 35
  • 1
Lapin

Clonalité

  • 59
  • 34
Polyclonal

Conjugué

  • 51
  • 8
  • 6
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PINK1 est non-conjugé

Application

  • 71
  • 51
  • 43
  • 20
  • 20
  • 6
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Épitope

    • 22
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    This antibody reacts to PINK1 (PARK6).

    Purification

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    Immunogène

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the N-terminal region of human Park6 (PINK1).

    Isotype

    Ig Fraction
  • Indications d'application

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène

    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

    Autre désignation

    PINK1

    Sujet

    Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.Synonyms: BRPK, PARK6, PINK-1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6, Serine/threonine-protein kinase PINK1, mitochondrial

    ID gène

    65018, 9606

    UniProt

    Q9BXM7

    Pathways

    Autophagy
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