ADRBK2 anticorps (C-Term)

N° du produit ABIN359044

Détail du produit anti-ADRBK2 anticorps

Antigène: ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRBK2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to GRK3.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human GRK3.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur ADRBK2

Antigène: ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))

Autre désignation: beta-ARK-2 / ADRBK2 (ADRBK2 Produits)

Synonymes: anticorps bark2, anticorps grk3, anticorps 4833444A01Rik, anticorps AI851927, anticorps AW551196, anticorps Adrbk-2, anticorps Bark-2, anticorps GRK3, anticorps BARK2, anticorps Grk3, anticorps si:dz221d18.1, anticorps G protein-coupled receptor kinase 3, anticorps GRK3, anticorps grk3, anticorps Grk3

Sujet: The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the ADRBK2 enzyme, also known as GRK3, has 85 % amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95 % similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.Synonyms: BARK2, Beta-adrenergic receptor kinase 2, G-protein-coupled receptor kinase 3, GRK3

ID gène: 157, 9606

UniProt: P35626

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling