ILK anticorps (C-Term)
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- Antigène Voir toutes ILK Anticorps
- ILK (Integrin-Linked Kinase (ILK))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ILK est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to ILK2/ILK1.
- Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ILK2/ILK1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ILK Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- ILK (Integrin-Linked Kinase (ILK))
- Autre désignation
- Integrin-Linked Protein Kinase (ILK Produits)
- Synonymes
- anticorps CG10504, anticorps CT29478, anticorps DmILK, anticorps Dmel\\CG10504, anticorps ILK, anticorps ilk, anticorps l(3)78Ca, anticorps p59, anticorps AA511515, anticorps ESTM24, anticorps zgc:65842, anticorps ILK-1, anticorps ILK-2, anticorps P59, anticorps p59ILK, anticorps Integrin linked kinase, anticorps integrin linked kinase, anticorps integrin linked kinase S homeolog, anticorps integrin-linked protein kinase, anticorps integrin-linked kinase, anticorps Ilk, anticorps ILK, anticorps ilk.S, anticorps CpipJ_CPIJ016644, anticorps Bm1_20815, anticorps Tsp_07213, anticorps Tsp_07224, anticorps Tsp_15354, anticorps ilk
- Sujet
- Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) is an ankyrin repeat containing 51 kDa receptor-proximate serine-threonine kinase (1), with a reported migration rate of 59K. This 451 amino acid protein interacts with the cytoplasmic domain of the beta-1 integrin subunit and contains sequence motifs found in pleckstrin homology domains capable of interacting with phosphoinositide lipids. ILK is an upstream regulator of Pi(3)K dependant activation of protein kinase B (PKB/AKT) and inhibition of glycogen synthase kinase 3 (GSK-3). ILK2 expression is associated with mediation of cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. ILK2 is overexpressed in some highly invasive tumor cell lines.Synonyms: 59 kDa serine/threonine-protein kinase, ILK, ILK-1, ILK-2, ILK1, ILK2, p59ILK
- ID gène
- 16202
- NCBI Accession
- NP_034692
- UniProt
- O55222
- Pathways
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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