STRADA anticorps (N-Term)

N° du produit ABIN359296

Détail du produit anti-STRADA anticorps

Antigène: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADA est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to LYK5.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LYK5.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur STRADA

Antigène: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Autre désignation: STRAD alpha / LYK5 (STRADA Produits)

Synonymes: anticorps fj99g05, anticorps zgc:56109, anticorps wu:fj99g05, anticorps lyk5, anticorps LYK5, anticorps NY-BR-96, anticorps PMSE, anticorps STRAD, anticorps Stlk, anticorps Lyk5, anticorps 2610019A05Rik, anticorps 6030402H20Rik, anticorps AI480680, anticorps E130112C09Rik, anticorps STE20-related kinase adaptor alpha, anticorps ste20-related kinase adaptor alpha, anticorps STRADA, anticorps strada, anticorps Strada

Sujet: LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.Synonyms: NY-BR-96, STE20-related adapter protein, STE20-related kinase adapter protein alpha, STRAD, STRADA

ID gène: 92335, 9606

UniProt: Q7RTN6

Pathways: AMPK Signaling