MKNK1 anticorps (N-Term)

N° du produit ABIN359308

Détail du produit anti-MKNK1 anticorps

Antigène: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MKNK1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to MKNK1.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MKNK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MKNK1

Antigène: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Autre désignation: MKNK1 (MKNK1 Produits)

Synonymes: anticorps MNK1, anticorps MKNK1, anticorps zgc:171912, anticorps 2410048M24Rik, anticorps Mnk1, anticorps MAPK signal-integrating kinase 1, anticorps mknk1, anticorps mnk1, anticorps MAP kinase interacting serine/threonine kinase 1, anticorps MAP kinase-interacting serine/threonine kinase 1, anticorps MAP kinase interacting serine/threonine kinase 1 S homeolog, anticorps MKNK1, anticorps mknk1, anticorps Mknk1, anticorps mknk1.S

Sujet: MKNK1 encodes a predicted 424-amino acid protein containing a sequence typical of the catalytic domain of serine/threonine kinases and a putative N-terminal nuclear localization signal sequence.C-terminal region of MKNK1 was phosphorylated and activated in vivo and in vitro by ERK1 and p38 MAP kinases, but not by JNK/SAPK. The activated ERK is essential for the activation of MKNK1 in insect cells. MKNK1 was activated following stimulation of HeLa cells with a variety of extracellular stimuli. MNK1 bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2, and also binds strongly to the stress-activated kinase, p38.Synonyms: MAP kinase-interacting serine/threonine-protein kinase 1, MNK1

ID gène: 8569, 9606

UniProt: Q9BUB5

Pathways: Signalisation MAPK, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor