RIPK3 anticorps (N-Term)

N° du produit ABIN359362

Cet anticorps Lapin Polyclonal détecte spécifiquement RIPK3 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour RIPK3 anticorps (N-Term) (ABIN359362)

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIPK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-RIPK3 anticorps

Épitope: AA 8-38, N-Term

Specificité: This antibody detects RIPK3 / RIP3 at N-term.

Purification: Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region (between 8-38aa) of human RIPK3 / RIP3.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur RIPK3

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Autre désignation: RIPK3 / RIP3

Sujet: The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3

Poids moléculaire: 56901 Da.

ID gène: 11035, 9606

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades