RIPK3 anticorps (AA 489-518)

N° du produit ABIN3032450

L’anticorps anti-RIPK3 Polyclonal Lapin est utilisé pour la détection de RIPK3 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour RIPK3 anticorps (AA 489-518) (ABIN3032450)

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIPK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-RIPK3 anticorps

Épitope: AA 489-518

Fonction: RIPK3 Antibody

Purification: Purified

Immunogène: A portion of amino acids 489-518 from the human protein was used as the immunogen for this RIPK3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the RIPK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RIPK3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur RIPK3

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Autre désignation: RIPK3

Sujet: RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades