Prohibitin 2 anticorps (Tyr248)

N° du produit ABIN359504

Détail du produit anti-Prohibitin 2 anticorps

Antigène: Prohibitin 2 (PHB2)

Épitope: Tyr248

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin 2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PHB2.

Purification: Protein A column, followed by peptide affinity purification.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y248 of human PHB2.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur Prohibitin 2

Antigène: Prohibitin 2 (PHB2)

Autre désignation: Prohibitin-2 (PHB2 Produits)

Synonymes: anticorps bcap37, anticorps zgc:73150, anticorps wu:fc28c08, anticorps PHB2, anticorps phb2, anticorps ATPHB2, anticorps F21M11.21, anticorps F21M11_21, anticorps prohibitin 2, anticorps DKFZp469N1310, anticorps BAP, anticorps BCAP37, anticorps Bap37, anticorps PNAS-141, anticorps REA, anticorps p22, anticorps bap37, anticorps prohibitin2, anticorps xphb2, anticorps AU044498, anticorps Bcap37, anticorps Bap, anticorps Bap-37, anticorps Bcap27, anticorps prohibitin 2a, anticorps prohibitin 2, anticorps prohibitin 2 S homeolog, anticorps phb2a, anticorps PHB2, anticorps phb2, anticorps phb2.S, anticorps Phb2

Sujet: PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.Synonyms: B-cell receptor-associated protein BAP37, BAP, BAP37, D-prohibitin, PHB2, REA, Repressor of estrogen receptor activity

Poids moléculaire: 33165 Da predicted from amino acid sequence. Theoretical pI: 9.83.

ID gène: 11331, 9606

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling