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TIE1 anticorps (N-Term)

TIE1 Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN359947
  • Antigène Voir toutes TIE1 Anticorps
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Épitope
    • 15
    • 10
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 93
    • 36
    • 33
    • 1
    Humain, Souris
    Hôte
    • 76
    • 18
    • 1
    Lapin
    Clonalité
    • 77
    • 18
    Polyclonal
    Conjugué
    • 35
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TIE1 est non-conjugé
    Application
    • 74
    • 45
    • 23
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects TIE1 at N-term.
    Purification
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TIE.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TIE1 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Autre désignation
    TIE1 (TIE1 Produits)
    Synonymes
    anticorps JTK14, anticorps TIE, anticorps D430008P04Rik, anticorps tie-1, anticorps tyrosine kinase with immunoglobulin like and EGF like domains 1, anticorps tyrosine kinase with immunoglobulin-like and EGF-like domains 1, anticorps tyrosine-protein kinase receptor Tie-1, anticorps endothelium-specific receptor tyrosine kinase 1, anticorps TIE1, anticorps Tie1, anticorps CpipJ_CPIJ018933, anticorps tie1
    Sujet
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: TIE, Tie-1, Tyrosine-protein kinase receptor Tie-1
    Poids moléculaire
    125089 Da
    ID gène
    7075, 9606
    UniProt
    P35590
    Pathways
    Signalisation RTK
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