TIE1 anticorps (N-Term)
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- Antigène Voir toutes TIE1 Anticorps
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TIE1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects TIE1 at N-term.
- Purification
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TIE.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TIE1 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- Autre désignation
- TIE1 (TIE1 Produits)
- Synonymes
- anticorps JTK14, anticorps TIE, anticorps D430008P04Rik, anticorps tie-1, anticorps tyrosine kinase with immunoglobulin like and EGF like domains 1, anticorps tyrosine kinase with immunoglobulin-like and EGF-like domains 1, anticorps tyrosine-protein kinase receptor Tie-1, anticorps endothelium-specific receptor tyrosine kinase 1, anticorps TIE1, anticorps Tie1, anticorps CpipJ_CPIJ018933, anticorps tie1
- Sujet
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: TIE, Tie-1, Tyrosine-protein kinase receptor Tie-1
- Poids moléculaire
- 125089 Da
- ID gène
- 7075, 9606
- UniProt
- P35590
- Pathways
- Signalisation RTK
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