TRIB1 anticorps (C-Term)
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- Antigène Voir toutes TRIB1 Anticorps
- TRIB1 (Tribbles Homolog 1 (TRIB1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TRIB1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to TRIB1.
- Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human TRIB1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TRIB1 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- TRIB1 (Tribbles Homolog 1 (TRIB1))
- Autre désignation
- TRIB1 (TRIB1 Produits)
- Synonymes
- anticorps TRIB1, anticorps c8fw, anticorps gig2, anticorps skip1, anticorps trb1, anticorps tribbles, anticorps C8FW, anticorps GIG2, anticorps SKIP1, anticorps TRB1, anticorps A530090O15Rik, anticorps TRB-1, anticorps Trb1, anticorps Gig2, anticorps tribbles pseudokinase 1, anticorps tribbles pseudokinase 1 L homeolog, anticorps tribbles homolog 1 (Drosophila), anticorps TRIB1, anticorps trib1, anticorps trib1.L, anticorps Trib1
- Sujet
- TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.Synonyms: C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1, Tribbles homolog 1
- ID gène
- 10221, 9606
- UniProt
- Q96RU8
- Pathways
- Smooth Muscle Cell Migration
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