SMAD4 anticorps (Ser277)
Aperçu rapide pour SMAD4 anticorps (Ser277) (ABIN360050)
Antigène
Voir toutes SMAD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Ser277
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Specificité
- This antibody reacts to SMAD4.
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S277 of human SMAD4.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western Blot: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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Autre désignation
- SMAD4
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Sujet
- SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.Synonyms: DPC4, Deletion target in pancreatic carcinoma 4, MAD homolog 4, MADH4, Mothers against DPP homolog 4, Mothers against decapentaplegic homolog 4, SMAD 4, SMAD family member 4, SMAD-4
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ID gène
- 4089, 9606
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UniProt
- Q13485
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Pathways
- Cycle Cellulaire, Chromatin Binding, Autophagy
Antigène
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